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SAVE THE DATE: Nov 6-9, 2025*/ Puerto Vallarta, Mexico

The 20th Annual Hook the Cure at Villa Premiere is nearly **SOLD OUT**! Due to overwhelming demand, we've secured a limited number of premium oceanfront rooms next door at the ALL-INCLUSIVE Buenaventura Grand Hotel, with full access to ALL Villa Premiere amenities, dining, and events. Contact ggreen@cff.org immediately for current availability.

We're thrilled to announce that Hook the Cure has raised an impressive $10.85 million net over our 20-year journey! This November, we return to Puerto Vallarta's beautiful shores to celebrate two decades of impact in the fight against cystic fibrosis. With our signature blend of world-class fishing, premium golf, luxury spa services, and all-inclusive accommodations—plus celebrity appearances and a headliner concert—it's no wonder this milestone event reached capacity so quickly.

Hook the Cure is known for exceptional auction items, and we invite you to contribute as a donor—whether offering condominium stays, gift cards, event tickets, jewelry, tech gadgets, or other items. Even if you cannot attend our sold-out celebration, your auction donation plays a vital role in our mission to find a cure. Download the auction form or use our donation link to join our cause and help continue making history in the fight against cystic fibrosis.​​​​​​​​​​​​​​​​

Once again, please email Gary Green to check current status!

  • Schedule information will be messaged via email on November 1, 2025.

 

CELEBRITY GUESTS

In addition to headliner, Lucas Hoge, Hook the Cure continues to attract some of baseball’s greatest players including Roger Clemens, Rick Honeycutt, Orel Hershiser and Matt Young. Thank you for going to bat and helping raise over $10.85 million net for the Cystic Fibrosis Foundation.

 

PROUDLY SPONSORED BY:

 

 

OUTSTANDING CORPORATE SUPPORTER

 
 

WHAT IS CYSTIC FIBROSIS?

Cystic fibrosis is a progressive, genetic disease that affects the lungs, pancreas, and other organs. There are close to 40,000 children and adults living with cystic fibrosis in the United States (and an estimated 105,000 people have been diagnosed with CF across 94 countries), and CF can affect people of every racial and ethnic group.

In people with CF, mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause the CFTR protein to become dysfunctional. When the protein is not working correctly, it’s unable to help move chloride -- a component of salt -- to the cell surface. Without the chloride to attract water to the cell surface, the mucus in various organs becomes thick and sticky. In the lungs, the mucus clogs the airways and traps germs, like bacteria, leading to infections, inflammation, respiratory failure, and other complications. For this reason, minimizing contact with germs is a top concern for people with CF.

 
 

ABOUT THE CYSTIC FIBROSIS FOUNDATION

We are fueled by a dedicated group of scientists, caregivers, donors, volunteers, and people with CF and their families who are united by a common goal: to find a cure for this devastating disease and help those with CF live longer, healthier lives. We are driven by a dream that one day, not one person will lose a life, child, sibling, parent, or friend to cystic fibrosis, and we are determined to succeed.

The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and to provide all people with CF the opportunity to lead long, fulfilling lives by funding research and drug development, partnering with the CF community, and advancing high-quality, specialized care.

The CF Foundation is the world's leader in the search for a cure for cystic fibrosis, and nearly every CF-specific drug available today was made possible with our financial support. We are a donor-funded, 501(c)(3) nonprofit that is fully accredited by the Better Business Bureau's (BBB) Wise Giving Alliance program.

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